Doctor of Philosophy in Biochemistry and Molecular Genetics

Major: BIOC
Degree Awarded: Ph.D.
Unit: GM
Program Webpage: http://louisville.edu/medschool/biochemistry/

Program Information

As teachers and scientists, the faculty of the Department of Biochemistry and Molecular Genetics (BMG) subscribe to the following missions:

  • Provide up-to-date and high-quality classroom and laboratory instruction in the discipline of biochemistry, molecular biology, and genetics to students at the University.
  • Conduct and publish research or other scholarship in areas that advance knowledge within the discipline, contribute to improving the human condition.
  • Train students and post-doctoral fellows in biochemical research.

Program Admission Procedure

Criteria and Mechanism for Selection

All applications must be submitted on-line (http://louisville.edu/graduate/apply). A complete application must have all the School of Interdisciplinary and Graduate Studies requirements. In addition to the SIGS requirements, the following criteria will be used as the basis for formal acceptance of students to the Ph.D. program in Biochemistry and Molecular Genetics. We use a holistic review process that considers experience and rigor of coursework as indicators for success in our program. Acceptance into the program requires approval unanimously by the department’s Graduate Executive Committee and by a majority of the IPIBS Admissions Committee.

  1. Transcripts of all course work.
  2. Grade point average:
  3. The Graduate Record Examination general test.
  4. At least two letters of recommendation.
  5. A personal statement of interest.
  6. Select applicants will be invited for a personal or Skype interview with members of the Department of Biochemistry and Molecular Genetics.

All students accepted into the BMG Ph.D. graduate program enter The Integrated Programs in Biomedical Sciences (IPIBS) program (http://louisville.edu/medicine/ipibs/about).

Program Overview

During Ph.D. training students receive considerable guidance from their mentor, committee, and faculty members of the department. However, students need to recognize that individuals who pursue a biomedical graduate degree are expected to take full responsibility for their own scientific and professional development and to seek out and utilize all available resources for that goal.

Annual progress reports to document that a student is in good standing within the BMG graduate program are required. The criteria for good standing in the graduate program are based on successful completion of milestones that indicate progression towards a degree. These milestones are the successful completion of:

  1. all coursework with a minimum GPA of 3.0.
  2. a minimum of two laboratory rotations.
  3. serve as a teaching assistant for 1 semester.
  4. two seminar presentations.
  5. Ph.D. qualifying exam.
  6. annual committee meetings with documented adequate progress in years 3 and beyond.
  7. annual research conferences in years 3 and beyond.

To fulfill all requirements for the Ph.D. degree a student must

  1. complete a body of novel research (dissertation).
  2. publish at minimum one 1st author manuscript.
  3. write and defend a doctoral dissertation that is acceptable by the dissertation committee and School of Interdisciplinary Graduate Studies.

Student Support

An IPIBS Fellowship will provide stipend support for the first 23 months. Support after the first 23 months is the responsibility of the individual student's dissertation advisor. Students are also encouraged to seek extramural support.

Guidance for the Student

The Director of the Biochemistry and Molecular Genetics Graduate Program will serve as the first year advisor to all incoming graduate students until a disserta­tion advisor (mentor) is selected. During the first year, all students will meet with all available faculty to discuss research projects and complete a minimum of two laboratory rotations to help select a lab and mentor After completion of lab rotations and before beginning the second year, the student will select a mentor, subject to the approval of the Graduate Executive Committee and the department Chair.

All required classes should be taken before the end of the student’s second year and must be completed before taking the Ph.D. Qualifying Exam (QE). Upon successful completion of all coursework, the student will move into MS candidacy. The format of the QE requires the student to write and orally defend a NIH-style grant proposal on a topic different from their own research. After successful completion of the QE, the student will be awarded a MS degree and move into Doctoral candidacy. A Dissertation Committee will be formed which will serve as the Reading Committee and Examining Committee.

Each student must give an annual presentation to the department. In year 1 this is a short lab rotation report, years 2 and 3 a formal seminar, and years 3 and beyond a research conference. In years 3 and beyond the student must have an annual meeting with his/her Dissertation Committee. After each meeting, the mentor will complete the Annual Progress Report and provide copies to the Committee members, the student and the Director of the Biochemistry and Molecular Genetics Graduate Program. To remain in good standing in the program the report from the mentor and Dissertation Committee must reflect satisfactory progress towards the degree.

Curriculum

Timeline to Ph.D. degree

Year 1

Required CoursesTitleHoursOther RequirementsElectives
Fall
BIOC 645Biochemistry I4Student Journal Club
BIOC 611Adv Techniques in BMB4Seminar attendance
BIOC 613Lab Rotation2
Spring
BIOC 647Biochemistry II4Student Journal Club
BIOC 667Cell Biology3Seminar attendance
BIOC 630Responsible Conduct of Research1
BIOC 613Lab Rotation2
Summer
BIOC 619Research6

Year 2

Fall
BIOC 668Mol Biol/Genetics4
BIOC 680Biomolecular Interactions2
BIOC 606seminar I1
BIOC 619Research3
Spring

BIOC 603

Sp. Topics -Grant Writing

2seminar attendance

BIOC 675

Cancer Biol.

BIOC 619

Research3-7Ph.D. Qualifying Exam

BIOC 661

Mol. Toxicol

Summer
MAST600Master's candidacy

Years 3-5

DOCT 600Doctoral candidacyAnnual Dissertation Advisory Comm Mtg
Annual Presentation (seminar II & Research Conferences)

Faculty

Ronald G. Gregg, Ph.D.
Professor

Chair

Alan Cheng, Ph.D.

Assistant Professor

Barbara J. Clark, Ph.D.
Associate Professor

Director of Graduate Studies

Brian F. Clem, Ph.D.
Assistant Professor

Director of Admissions

Marsha Cole, Ph.D.

Assistant Professor

Jaydev N. Dholakia, Ph.D.

Associate Professor

Steven R. Ellis, Ph.D.

Professor

Pamela W. Feldhoff, Ph.D.

Associate Professor

Ted Kalbfleisch, Ph.D.

Associate Professor

Carolyn M. Klinge, Ph.D.

Professor

David Samuelson, Ph.D.

Associate Professor

Eugenia Wang, Ph.D.
Professor
Gheens Endowed Chair on Aging
Corey Watson, Ph.D.
Assistant Professor

 

Emeritus Faculty

William L. Dean, Ph.D.

Professor

Richard C. Feldhoff, Ph.D.

Professor

Thomas E. Geoghegan, Ph.D.

Professor

Russell A. Prough, Ph.D.

Professor

James L. Wittliff, Ph.D.
Professor

 

Associate Faculty

Shahid Baba, Ph.D.

Assistant Professor

Paula J. Bates, Ph.D.

Associate Professor

Aruni Bhatnagar, Ph.D.

Professor

Douglas Borchman, Ph.D.

Professor

Matt Cave, M.D.

Associate Professor

Jonathan Chaires, Ph.D.
Professor

Jason Chesney, Ph.D., M.D.

Professor

Daniel J. Conklin, Ph.D.

Assistant Professor

Nichola Garbett, Ph.D.

Assistant Professor

Bradford Hill, Ph.D.

Assistant Professor

Kyung Hong, Ph.D.

Assistant Professor

Gary W. Hoyle, Ph.D.

Professor

Alfred Jensen, M.D.

Professor

Jon B. Klein, Ph.D.

Professor

Amanda Jo LeBlanc, Ph.D.

Assistant Professor

Donghan Lee, Ph.D.

Associate Professor

Zhenmin Lei, Ph.D., M.D.

Professor

Qiutang Li, Ph.D.

Assistant Professor

Mark Linder, Ph.D.

Associate Professor

Qingxian Lu, Ph.D.

Assistant Professor

Kenneth R. McLeish, M.D.

Professor

Joseph Moore, IV, Ph.D.

Assistant Professor

Donald H. Miller, M.D., Ph.D.
Professor

Robert A. Mitchell, Ph.D.

Associate Professor

Timothy O'Toole, Ph.D.

Assistant Professor

David W. Powell, Ph.D.

Associate Professor

Madhavi Rane, Ph.D.

Associate Professor

Sanjay Srivastava, Ph.D.

Professor

Shigeo Tamiya, Ph.D.

Assistant Professor

Sucheta Telang, M.D.

Associate Professor

John O. Trent, Ph.D.

Professor

Roland Valdes Jr., Ph.D.

Professor

Stephen J. Winters, M.D.

Professor