Targeting the anaphase promoting complex as lung
KY Lung Cancer Research Program, 5/01/2015 – 4/30/17
This project will determine the mode of action of compounds targeting the APC/C in inducing cell death in lung cancer cells and will optimize the most potent compound identified thus far.
Differential miRNA expression in arsenic-induced
NIH/NIEHS R21ES023627, 07/01/2015- 06/30/2017 (anticipated)
The aims of this project are to profile differential miRNA expression in arsenic induced skin lesions and cancers and in keratinocytes during transformation by chronic arsenic exposure.