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Review Criteria for CEGIB Pilot Grants

The Center for Environmental Genomics and Integrative Biology is funded by an NIEHS P30 grant, and follows NIEHS guidelines for Pilot Grants. The goals of the CEGIB Pilot Project Program are to provide seed funding for projects that will address environmental health issues. This is seen broadly as environmental effects on disease, especially as studied by genomics or systems biology approaches.

All proposals are reviewed by scientists from around the world with relevant expertise, and also reviewed by a local faculty committee.  To receive funding, proposals MUST be judged to meet the following criteria:
     • High scientific merit (demonstrated by strong innovation, a careful and appropriate experimental design, a novel research direction).
     • Clear importance to Environmental Health Sciences.
     • Focus on significant gaps in environmental –omics, integrative or systems biology.
     • High potential for leading to external funding, especially NIEHS R01 applications, and publications.

In addition, review criteria reflect CEGIB goals to give preference to:
     • New investigators, especially in collaboration with an experienced environmental researcher.
     • Research that supports the CEGIB focus areas of Environmental Cardiology, Environmental Carcinogenesis, and/or Developmental origins of disease.
     • Projects which make good use of CEGIB Facilities Cores.
     • Research in which investigators from other areas focus on environmental health research, especially in collaboration with an experienced  environmental researcher.

Projects should make use of a CEGIB Facilities Core and applicants are expected to contact the Core's Director for consultation on the use of the facility core and procurement of a letter of support.

  • Bioinformatics Biostatistics & Computational Biology Core (link)  Director, Dr. Nigel Cooper (email)
  • Proteomics Biomarker Discovery Core (link) Director, Dr. Jon B. Klein (email)
  • Integrative Health Sciences Core (link) Director, Dr. David J. Tollerud (email

 

Note: CEGIB has a broad view of what constitutes “environmental health science” consistent with NIEHS guidelines. Pilot grant proposals should seek to understand how environmental exposures interact with biological processes.  Some examples of environmental exposures relevant to NIEHS include industrial chemicals or manufacturing by-products, metals, pesticides, herbicides, air pollutants and other inhaled toxicants (including second-hand smoke), particulates or fibers, fungal or bacterially derived toxins due to ambient exposures. Pilot grant proposals should not focus on agents outside the mission of NIEHS such as drugs of abuse, or smoking (except second-hand smoke).  Please see the NIEHS website for common diseases and conditions that evidence shows may be strongly linked to environmental exposures (link)

 

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