The development of the Diabetes and Obesity Center has had a major impact on cardiovascular medicine, as well as diabetes and obesity research. By providing relevant core support, cultivating research infrastructure and recruiting a critical mass of investigators, the Center has enabled collaborative interactions between complementary projects.

These interactions have been essential as we acquire new research funding, and develop comprehensive and multi-disciplinary projects.

Building on the infrastructure provided by the Center, and with the help of junior investigators, members of the Center have obtained funding for several large multi-investigator projects, such as an NIH Program Project Grant (PPG), a multi-PI grant from the National Institute of Environmental Health Science (NIEHS), and an National Heart, Lung, and Blood Institute-supported pre-clinical consortium to develop a regional clinical center for the Cardiovascular Cell Therapy Research Network (CCTRN).

The Center has also built and acquired new research space with four state-of-the-art research cores, providing support for flow cytometry, imaging, pathology, cardiac function, animal maintenance and the development of new animal models of diabetes and obesity.

In addition to providing expert assistance for these challenging techniques, our cores have developed novel assays and procedures, lending our investigations a unique edge. As a result of these advances, the Center continues to flourish.

New investigators have been recruited to the Center. Member numbers have increased from 30 to 60, and have published landmark studies in diverse areas, including diabetes, obesity and cardiovascular research, stem cell biology and environmental cardiology.

This current membership represents a unique mix of complementary expertise that is not only well-aligned with the central focus of our Center, but is also well-positioned for its future success.