The following (if applicable) are required for DEHS Approval for the use of hazardous chemicals:

1. Completed UofL Chemical Hygiene Plan (CHP) and submitted to DEHS. For instructions see-

   Chemical Hygiene Plan
   

2. Completed chemical inventory and submitted to DEHS. For guidance see-

   Chemical Inventory
   

3. Standard Operating Procedures (SOPs) for all “Highly Hazardous Chemicals” involved in this proposal have been prepared. “Highly Hazardous Chemicals” are carcinogens, reproductive toxins, and chemicals with a high degree of acute toxicity. For more information see-

   Written Safety Procedures – SOP’s and SASP’s
   

4. Special Animal Safety Protocols (SASPs) are required when hazardous drugs or toxic chemicals or their hazardous metabolites could be excreted from the animals contaminating the bedding materials. For more explanation and already prepared standardized SASPs see-

   Written Safety Procedures – SOP’s and SASP’s
   

5. All project participants who will be working with chemicals attended Lab Safety/Hazardous Waste Training provided by DEHS. See your completed Chemical Hygiene Plan cover sheet for training dates.

   Lab Safety/Hazardous Waste Training
   

6. Halogenated liquid anesthetic agents, i.e., isoflurane, halothane have been identified as producing waste anesthetic gases (WAGs) which are considered reproductive toxins. DEHS conducts leak detection on all anesthesia systems at UofL. For work practices that should be used to prevent waste anesthetic gas exposure see-

   Waste Anesthetic Gases