CTSI Research Development Core
(Biostatistics, Methodology and Ethics)
The CTSI Research Development Core is led by:
Mark A. Rothstein, JD., Professor.
Mark A. Rothstein, JD, Herbert F. Boehl Chair of Law and Medicine, serves as Director of the Research Development Core. Prof. Rothstein is an expert on research ethics, genetics, and health privacy. From 1999-2008, he chaired the Subcommittee on Privacy and Confidentiality, National Committee on Vital and Health Statistics, the statutory advisory committee to the Secretary of HHS on health information policy. He is past-president of the Am. Soc. of Law, Medicine and Ethics, and has served as an adviser to federal and state governments on a wide range of health and bioethics issues.
David J. Doukas, MD, Co-director (Bioethics), is the William Ray Moore Endowed Chair of Family Medicine and Medical Humanism and Prof. and Chief of the Div. of Medical Humanism and Ethics (DMHE) in the Dept. of Family and Community Medicine. He is also chair of the University Hospital Ethics Committee. He is an internationally-known scholar of empirical bioethics in community settings, on issues ranging from end-of-life care to genetics and prenatal testing.
Richard N. Baumgartner, PhD, Co-director (Epidemiology) is Prof. and Chair of Epidemiology and Population Health at UofL and Distinguished University Scholar. He has extensive experience in the design/conduct of prospective cohort studies. He was the PI of a longitudinal study of changes in nutrition, body composition, physical and cognitive function in elderly men and women, from 1994-2004. He also is one of the founding PIs of the "Health, Eating, Activity and Lifestyle" (HEAL) Study, a case-cohort study of 1,100 women with breast cancer that is now entering its 12th year of continuous follow-up. He is an internationally recognized expert in the nutritional and molecular epidemiology of aging and chronic disease with over 200 journal articles and book chapters. His current research is in body composition (obesity, sarcopenia and osteopenia) related to aging, chronic disease and disability, and nutritional, hormonal and inflammatory biomarkers in the molecular epidemiology of breast cancer.
Susmita Datta, PhD, Co-director (Biostatistics) is Prof. of Bioinformatics and Biostatistics and a University Scholar. She is an elected member of the International Statistical Institute. She serves as editor/associate editor/editorial board member for a number of statistics and bioinformatics journals. She is currently PI on 2 projects (NIH, NSF) and Co-Investigator on NIH P30, P01 projects. She has extensive experience in population biology, statistical genetics, ‘omics analysis, infectious disease modeling and survival analysis. Her bioinformatics interests span transcriptomics (microarray data analysis), proteomics (MALDI-MS, MALDI-MS/MS, SELDI data) and metabolomics. Her current research involves development of new methodology for high dimensional data analysis using modern multivariate clustering/ classification techniques and statistical inference, especially biomarker identification of cardiovascular disease and kidney disease. She generated her own proteomic data to detect biomarker(s) of fetal alcohol related disorder. She also serves as Biostatistician for the UofL Alcohol Research Center and Biostatistics group leader at CEGIB.
Our Goals are to:
•Educate investigators in clinical and translational research.
•Health Outcomes Research
•Support clinical and translational research initiatives
BIOSTATISTICAL CONSULTING SERVICE (all others)
Guy Brock, PhD