Division: Analytical Chemistry Specialty: Bioinformatics & Bioanalytical Chemistry Phone: 502-852-8878 Email: xiang.zhang@louisville.edu Website: Zhang Group Web Page

1989 B.S.   Lanzhou University
1994 M.S.  Institute of Modern Physics, Chinese Academy of Sciences
2001 Ph.D. Purdue University

We are interested in multidisciplinary life sciences research. Our expectation is that the chemistry of biomolecules in living systems can define disease mechanisms. We would like to tell the biological story revealed by these molecules with advanced bioinformatics methodologies and modern analytical techniques. Our bioanalytical research exploits practical and efficient high-throughput technologies for the analyses of complex mixtures derived from living systems. The bioinformatics research in our group develops informatics system that enables mining of high throughput data for identification of molecular networks and ‘systems level’ knowledge assembly.

Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry peak sorting algorithm
Cheolhwan Oh, Xiaodong Huang, Fred E. Regnier, Charles Buck, Xiang Zhang
J. Chromatogr. A  2008, 1179, 205-215.

A hierarchical statistical model to assess the confidence of peptide and protein identifications made by tandem mass spectrometry
Changyu Shen, Ziping Wang, Ganesh Shankar, Xiang Zhang, Liang Li
Bioinformatics 2008, 24, 202-208.

Neural network prediction of peptide behavior in strong anion exchange chromatography
Cheolhwan Oh, Stanislaw H. Zak, Hamid Mirzaei, Fred E. Regnier, Xiang Zhang
Bioinformatics 2007, 23, 114-118.

Current status of computational approaches for protein identification using tandem mass spectra
Xiang Zhang, Cheolhwan Oh, Paige C. Riley, Charles Buck
Current Proteomics 2007, 4, 121-130.