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Muriel C. Maurer

Professor

Muriel C. Maurer
Division: Biochemistry
Specialty: Protein Structure-Function
Phone: 502-852-7008
Email: muriel.maurer@louisville.edu
Website: Maurer Group

Education and Research Experience

1987 B.A.   Goucher College
1993 Ph.D. University of Virginia
1992-1995 Cornell University, NIH Postdoctoral Fellow
1995-1996 Cornell University, Postdoctoral Fellow
1996-1997 Cornell University, Research Associate
 Fall 2007   Honorary Senior Research Fellow
                   Leeds Institute of Genetics, Health, and Therapeutics (LIGHT) 

Research Interests

See website.

Publications (recent or significant)

A non-reactive glutamine residue of alpha-antiplasmin promotes interactions with the factor XIIIa active site region.
Cleary, D.B., Doiphode, P.G., Sabo, T. M., Maurer, M. C.
J. Thromb. Haemost. 2009, in press

Biophysical Investigation of GpIbα Binding to Thrombin Anion Binding Exosite II
Sabo, T. M., Maurer, M. C.
Biochemistry 2009, 48, 7110–7122

Perturbations in Factor XIII Resulting From Activation and Inhibition Conditions Examined by Solution Based Methods and Detected by MALDI-TOF MS
Sabo, T. M., Brasher, P. B., Maurer, M. C.
Biochemistry 2007, 46, 10089-10101

Employing Mutants to Study Thrombin Residues Responsible for Factor XIII Activation Peptide Recognition:  A Kinetic Study
Isetti, G., Maurer, M. C.
Biochemistry 2007, 46, 2444-2452

Conformational Analysis of y' peptide (410-427) Interactions with Thrombin Anion Binding Exosite II
Sabo, T. M., Farrell, D. H., Maurer, M. C.
Biochemistry 2006, 45, 7434-45

Characterizing the Specificity of Activated Factor XIII for Glutamine-Containing Substrate Peptides
Cleary, D. B., Maurer, M. C.
Biochim Biophys Acta
 2006, 1764, 1207-17

Probing Interactions Between the Coagulants Thrombin, Factor XIII, and Fibrin(ogen)
Maurer, M. C., Trumbo, T. A., Isetti, G., Turner, B. T. Jr.
Archives of Biochemistry and Biophysics  2006, 445, 36-45

Mapping of Factor XIII Solvent Accessibility as a Function of Activation State Using Chemical Modification Methods
Turner, B. T. Jr, Sabo, T. M., Wilding, D., Maurer, M. C.
Biochemistry 2004, 43, 9755-9765

Thrombin Activity is Unaltered by N-terminal Truncation of Factor XIII Activation Peptides
Isetti, G., Maurer, M. C.
Biochemistry 2004, 43, 4150-4159

Probing Thrombin's Activity to Accommodate a V34F Substitution Within the Factor XIII Activation Peptide Segment (28-41)
Isetti, G., Maurer, M. C.
J. Peptide Research 2004, 63, 241-252
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