Eugene G. Mueller
Professor
Charles L. Bloch Professor
 |
Division: Biochemistry
Specialty: Mechanistic Enzymology Phone: 502-852-5811 Email: eugene.mueller@louisville.edu Website: Mueller Research Group |
Education and Research Experience
1987 B.S. University of Illinois–Urbana
1992 Ph.D. Harvard University
1992 Ph.D. Harvard University
Research Interests
Enzymology
tRNA Modification
Sulfur Transfer
Bioorganic Mechanism
tRNA Modification
Sulfur Transfer
Bioorganic Mechanism
Publications (recent or significant)
Crystal Structure of Pseudouridine Synthase RluA: Indirect Sequence Readout through Protein-Induced RNA Structure
C. Hoang, J. Chen, C. A. Vizthum, J. M. Kandel, C. S. Hamilton, E. G. Mueller, and A. R. Ferré-d'Amaré
Mol. Cell 2006, 24, 535-545
Mechanistic Investigations of the Pseudouridine Synthase RluA Using RNA Containing 5-Fluorouridine
C. S. Hamilton, T. M. Greco, C. A. Vizthum, J. M. Ginter, M. V. Johnston, and E. G. Mueller
Biochemistry 2006, 39, 12019-12038
Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis
C. M. Wright, G. D. Christman, A. M. Snellinger, M. V. Johnston, and E. G. Mueller
Chem. Comm. 2006, 3104-3106
Trafficking in persulfides: delivering sulfur in biosynthetic pathways
E. G. Mueller
Nature Chem. Biol. 2006, 4, 185-194
C. Hoang, J. Chen, C. A. Vizthum, J. M. Kandel, C. S. Hamilton, E. G. Mueller, and A. R. Ferré-d'Amaré
Mol. Cell 2006, 24, 535-545
Mechanistic Investigations of the Pseudouridine Synthase RluA Using RNA Containing 5-Fluorouridine
C. S. Hamilton, T. M. Greco, C. A. Vizthum, J. M. Ginter, M. V. Johnston, and E. G. Mueller
Biochemistry 2006, 39, 12019-12038
Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis
C. M. Wright, G. D. Christman, A. M. Snellinger, M. V. Johnston, and E. G. Mueller
Chem. Comm. 2006, 3104-3106
Trafficking in persulfides: delivering sulfur in biosynthetic pathways
E. G. Mueller
Nature Chem. Biol. 2006, 4, 185-194
2013 John Richard Binford Memorial Award
