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Guy Brock

Active Grants

"Molecular Determinants of Developmental Defects" (PI - R.M. Greene)
NIH 2P20-RR017702-06, Center of Biomedical Research Excellence (COBRE)

Project Title: Integrated Analysis of RNA Expression During Orofacial Development

Role: Co-PI of subproject (with P. Mukhopadhyay) (20% time and effort)
Term: 01/01/11-05/31/13

"Molecular Determinants of Developmental Defects" (PI - R.M. Greene)
NIH 2P20-RR017702-06, Center of Biomedical Research Excellence (COBRE)
Role: Co-Investigator/Biostatistician (20% time and effort)
Term: 2007- 2012

"Transcriptional Coactivators and Pregnancy Outcomes" (PI - R.M. Greene)
NIH R01HD053509
Role: Co-Investigator/Biostatistician (8% time and effort)
Term: 2007- 2012

"Nutritional Epigenetics and Orofacial Development" (PI - R.M. Greene)
NIH R01DE018215
Role: Co-Investigator/Biostatistician (9% time and effort)
Term: 2009-2013

“Microbiology Testing with the Aim of Directed Antimicrobial Therapy for Community-Acquired Pneumonia (CAP)”

HHSN272201000040C (V Yu, Univ of Pittsburgh)


Role: Co-Investigator/Biostatistician. (20% time and effort)

Term: 01/01/13 – 12/31/17




·  Hertweck SP, Yoost JL, McClure ME, Siow Y, Brock G, Wintergerst KA, Fallat ME. "Ferriman-Gallwey Scores, Serum Androgen and Mullerian Inhibiting Substance Levels in Hirstute Adolescent Girls" (accepted to J of Pediatric Adolescent Gynecology).

·  Cannon RM, Brock GN , Marvin MR, Slakey DP, Buell JF. "A Decade of Disparity: Differences in Donor Quality for African American And Caucasian Recipients of Cadaveric Renal Transplants from 2000 to 2010" (accepted to American Journal of Transplantation)

·  Alton TM, Brock G, Yang D, Wilkings D, Hertweck P, and Loveless MB (2012). "Retrospective Review of Intrauterine Device in Adolescent and Young Women" Journal of Pediatric and Adolescent Gynecology 25(3):195-200.

·  Lavender NA, Rogers EN, Yeyeodu S, Rudd J, Hu T, Zhang J, Brock GN , Kimbro KS, Moore JH, Hein DW, Kidd LR. (2012) "Interaction among Apoptosis-Associated Sequence Variants and Joint Effects on Aggressive PCA" BMC Medical Genomics 5(1):11. [Epub ahead of print]

·  Cannon RM, Brock G, Marvin MR, Eng M, Buell JF (2012). "Analysis of BK Viral Infection After Alemtuzumab Induction for Renal Transplant", Transplant Infectious Disease 14(2):142-9.

·  Muenyi CS, Pinhas AR, Fan TW, Brock GN , Helm CW, and States JC (2012). "Sodium arsenite ± hyperthermia sensitize p53 expressing human ovarian cancer cells to cisplatin by modulating platinum DNA damage responses." Toxicological Sciences 127(1):139-49.

·  Mukhopadhyay P, Singh S, Brock G, Pisano MM, and Greene RM. (2012) "Strain-specific modifier genes governing craniofacial phenotypes in ski-null mice" Birth Defects Research Part A 94(3):162-75.

·  Cannon RM, Brock G, Buell JF (2012). "Surgical Resection for Hilar Cholangiocarcinoma: Experience improves Resectability", HPB 14(2):142-9.

·  Lutz PM, Kelty EA, Brown TD, Wilson TJ, Brock G, Neal R. (2012) "Environmental Cigarette Smoke exposure Modulates IgE levels of Pb-exposed Children", Toxicology 291(1-3):43-50.


·  Brock GN , Barnes CN, Ramirez JA, Myers JA (2011). "How to handle mortality when investigating length of hospital stay and time to clinical stability" BMC Med Res Methodol. 11(1):144.

·  Brock GN , Mostajabi F, Ferguson N, Carrubba CJ, Eng M, Buell JF, Marvin MR (2011). "Prophylaxis against denovo hepatitis B for liver transplantation utilizing Hep B core(+) donors: does HBIG provide a survival advantage?" Transplant Int. 24(6):570-81.

·  Oh S, Kang DD, Brock GN* , Tseng GC* (2011) "Biological impacts of missing value imputation on down-stream analyses in microarray data" Bioinformatics 27(1):78-86.

·  Lu C, Hallgren JJ, Lin Y, Black DS, Ekstrom LC, Fentie IH, Brock G, Song Y, Winstead WI, Roisen FJ (2011). "Human olfactory-derived neural progenitors diminish locomotory deficits following spinal cord contusion injury" Journal of Neurodegeneration and Regeneration 4(1):33-50.

·  Cannon RM, Brock G, Buell JF (2011). "A Novel Classification System to Address Financial Impact and Referral Decisions for Bile Duct Injury in Laparoscopic Cholecystectomy" HPB Surgery , 2011:371245.

·  Bordon J, Plankey MW, Young M, Greenblatt RM, Villacres MC, French AL, Zhang J, Brock G, Appana S, Herold B, Durkin H, Golub JE, Fernandez-Botran (2011). "Lower levels of interleukin-12 precede the development of tuberculosis among HIV-infected women" Cytokine, 56(2):325-31. PMID: 21880503.

·  Mukhopadhyay P, Brock GN , Appana S, Webb C, Greene RM, and Pisano MM (2011). "Developmental microRNA expression profiling of murine neural tube" Birth Defects Research Part A, 91(8):744-62. PMID: 21770019.

·  Cannon RM, Brock GN , Marvin MR, Buell JF (2011). "Laparoscopic Liver Resection: An Examination of Our First 300 Patients" J Am Coll Surg, 213(4):501-7. PMID: 21624840.

·  Ramsey TL, Meltzer HY, Brock GN , Mehrotra B, Jayathilake K, Bobo WV, Brennan MD (2011). "Evidence for a SULT4A1 haplotype correlating with baseline psychopathology and response to atypical antipsychotics in schizophrenia and related disorders" Pharmacogenomics 12(4):471-80.

·  Gobejishvili L, Avila DV, Barker DF, Ghare S, Henderson D, Brock GN , Kirpich IA, Joshi-Barve S, Mokshagundam SP, McClain CJ, Barve S (2011). "S-Adenosylmethionine Decreases LPS-Induced Phosphodiesterase 4B2 and Attenuates TNF Expression via cAMP/PKA Pathway" J Pharmacol Exp Ther 337(2):433-43.

·  Kidd LCR, Templeton TM, Doll M, Srivastava D, Thacker B, Komolafe O, Pihur V, Brock G, and Hein DW (2011). "No association between variant N-acetyltransferase genes, cigarette smoking and prostate cancer susceptibility among men of African descent" Biomarkers in Cancer 3:1-13.

·  Warner DR, Mukhopadhyay P, Brock GN , Pihur V, Pisano MM, Greene RM (2011). "TGFB and Wnt-3a interact to induce unique gene expression profiles in murine embryonic palate mesenchymal cells" Reproductive Toxicology 31(2):128-33.

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