Recent Publications

Fungal Research

Relevant Publications

Wang, L. and M. H. Perlin. 1998. Isolation of a novel gene (HSGc11) whose expression is apparently limited to the hyphal stage of Microbotryum violaceum. Int. J. Plant Sci. 159:206-212.

Shi, T.-L. and M.H. Perlin. 2001. The beta-tubulin-encoding gene from Microbotryum violaceum:  unusual in a variety of ways. Curr. Genet.39: 253-263

Freeman, A.B., Duong, K.K., Shi, T.-L., Hughes, C.F., and Perlin, M.H. 2002. Isolates of Microbotryum violaceum from North America are distinct from their European counterparts. Mol. Phylogenet. Evol.23:158-170.

Smith, D.G., Garcia-Pedrajas, M.D., Gold, S.E., and Perlin, M.H. 2003. Isolation and Characterization  from Pathogenic Fungi of Genes encoding Methylammonium Permeases and their roles in Dimorphism. Mol. Micro.50:259-275.

Smith,D., Hong, W., Garcia-Pedrajas, M.D., Gold, S.E., and Perlin, M.H. 2004. A ste20 homologue in Ustilago maydis plays a role in dimorphism and pathogenicity. Euk. Cell3:180-189.

Hughes, C.F., and M.H. Perlin. 2005. Differential expression of mepA, mepC, and smtE during growth and development of Microbotryum violaceum. Mycologia 97: 605-611.

Kämper, J., R.Kahmann, M.Bölker, B. J.Saville, F.Banuett, J. W.Kronstad, S. E.Gold, M.H. Perlin et al. 2006. Living in pseudoharmony: the genome of the biotrophic fungus Ustilago maydis. Nature, 444:97-101.

Klosterman, S.J.,  M.H. Perlin, M. Garcia-Pedrajas, S. F. Covert and S. E. Gold. 2007. Genetics of morphogenesis and pathogenic development of Ustilago maydis. Adv Genet. 57:1-47.

Garcia-Pedrajas, M.D., M.  Nadal, L. B Kapa, M.H. Perlin, D. L. Andrews, S. E. Gold. 2008.DelsGate, a robust and rapid gene deletion construction method. Fungal Genetics Biol.45:379-388.

Garcia-Pedrajas, M.D., M.  Nadal, M. Bölker, S. E. Gold, M.H. Perlin. 2008. Sending mixed signals: Redundancy vs. uniqueness of signaling components in the plant pathogen, Ustilago maydis. Fungal Genetics Biol. 45(Supplement 1):S22-S30.

Pham, C.D., Z, Yu, B. Sandrock, M. Bölker, S. E. Gold, and M.H. Perlin. 2009.Ustilago maydis Rho1 and 14-3-3 homologues participate in pathways controlling cell separation and cell polarity. Eukaryot. Cell,  8:977-989.

Pham, C.D. and M.H. Perlin. 2010. Possible additional roles in mating for Ustilago maydis Rho1 and 14-3-3 homologues. Communicative and Integrative Biology. 3(1):57 - 59 DOI: 10.4161/cib.3.1.9864

Garcia-Sanchez MA, Martin-Rodrigues N, Ramos B, Vega-Bartol JJ, Perlin MH, Diaz-Minguez JM. 2010. fost12, the Fusarium oxysporum homologue of the transcription factor Ste12, is upregulated during plant infection and required for virulence.  Fungal Genet. Biol. 47(3):216-25

Pham, C.D., J.T. Dixon and M.H. Perlin. 2010. The many and varied roles of Rho GTPases in fungi and a comprehensive review of their regulation. Curr. Trends in Microbiol. 5:1-17

Agarwal, C, D J Schultz and M.H. Perlin. 2010.  Two phosphodiesterases from Ustilago maydis share structural and biochemical properties with non-fungal phosphodiesterases. Front. Microbio., doi: 10.3389/fmicb.2010.00127

Lovely, C.B., K.B. Aulakh, and M.H. Perlin. 2011. The Role of Hsl7 in Morphology and Pathogenicity and its Interaction with other Signaling Components in the Plant Pathogen, Ustilago maydis. Eukaryot. Cell 11:869-883.

Lovely, C.B. and M.H. Perlin. 2011.  Cla4, but not Rac1, regulates the filamentous response of Ustilago maydis to low ammonium conditions. Communicative and Integrative Biology. 4(6):1-4.

Pham, C.D., Z. Yu, C. B. Lovely, C. Agarwal, D. A. Myers, J. A. Paul, M. Cooper, M. Barati, and M.H. Perlin. 2012. Haplo-insufficiency for different genes differentially reduces pathogenicity and virulence in a fungal phytopathogen. Fungal Genet. Biol. Online publication complete: 15-DEC-2011 DOI information: 10.1016/j.fgb.2011.11.007

Petit, E., T. Giraud, D. M. de Vienne, M. A. Coelho, G. Aguileta, J. Amselem, J. Kreplak, J.Poulain, F. Gavory, P. Wincker, S. K. Young, C. Cuomo, M.H. Perlin, and M. E. Hood. 2012. Linkage to the mating-type locus across the genus Microbotryum: insights into nonrecombining chromosomes. Evolution Published online 26 June 2012 doi:10.1111/j.1558-5646.2012.01703.x

Agarwal, C., K. B. Aulakh, K. Edelen, M. Cooper , R. M. Wallen, S. Adams, D. J. Schultz, and M.H. Perlin. 2013. Ustilago maydis phosphodiesterases play a role in the dimorphic switch and in pathogenicity. Microbiology 159(Pt 5):857-68. doi: 10.1099/mic.0.061234-0. Epub 2013 Mar 8. PMID:23475947[PubMed - in process]



Evolution of Antibiotic Resistance

Relevant Publications

Dugatkin, L.A., M.H. Perlin and R.M. Atlas. 2003. The evolution of group-beneficial traits in the absence of between-group selection J. Theoret. Biol. 220:67-74.

Nurizzo, D., Shewry, S.C., Perlin, M.H., Brown, S.A., Dholakia, J.N., Fuchs, R.L., Dava, T., Baker, E.N., Smith, C.A. 2003. The crystal structure of aminoglycoside-3’-phosphotransferase-IIa, an enzyme responsible for antibiotic resistanceJ. Mol. Biol. 327:491-506.

Dugatkin, L.A., Perlin, M.H., Lucas, J.S. and Atlas, R.M. 2005. Group-beneficial Traits, Frequency-Dependent Selection and Genotypic Diversity: An Antibiotic Resistance Paradigm . Proc. Roy. Soc. London. 272:79-83.

Dugatkin, L.A., M.H. Perlin,, and R.M. Atlas. 2005. Antibiotic resistance and the evolution of group-beneficial traits. II: A metapopulation model.J. Theoret. Biol. 236:392-6.

Dugatkin, L.A., Dugatkin, A.D., Atlas, R.M., Perlin, M.H. 2008 Cheating on the Edge. PLoSOne3, e2763.

Clark, D.R., Alton, T.M., Bajorek, A., Holden, P., Dugatkin, L.A., Atlas, R.M. & Perlin, M.H. 2009 Evolution of altruists and cheaters in near-isogenic populations of Escherichia coli. Frontiers in BioSciences14, 4815-4824.

Perlin, MH, D. R. Clark, C. McKenzie, H. Patel, N. Jackson, C. Kormanik, C. Powell, A. Bajorek, D. A. Myers, L. A. Dugatkin, and R. M. Atlas. 2009. Protection of Salmonella by ampicillin-resistant E. coli in the presence of otherwise lethal drug concentrations. Proc. Roy. Soc. London.

Brown, S.A., J.N. Dholakia, and M.H. Perlin. 2010.. Photoaffinity labeling of Aminoglycoside Phosphotransferase 3’-II with azido ATP confirms the involvement of conserved lysine in ATP binding.J Biochem Tech 2(4):190-195. Published online: 8 February 2011,© Sevas Educational Society 2008-2010