The UofL Alcohol Research Center well represented at RSA 2019
“Cathelicidin Deficiency Exacerbates Alcohol-Induced Liver Injury via Uric Acid-Mediated Inflammasome Activation”. F Li, V Vatsalya, C McClain, W Feng
“Metagenomic analyses reveal a significant enrichment of “pro-inflammatory” Enterobacteriaceae associated with very heavy alcohol use and HIV infection”. R Singhal, R Smith, K Stocke, S Ghare, M Vadhanam, D Lioznov, E Krupitsky, K Armah, N Gnatienko, J Samet, K Bryant, C McClain, M Freiberg, S Barve
“Association of elevated uric acid with liver injury, gut-barrier dysfunction and inflammation; and efficacy of abstinence, treatment with thiamine in early alcoholic liver disease”. V Vatsalya, A Sutrawe, F Li, M Mishra, N Shah, W Feng, CJ McClain
“Sulforaphane Protects Against Ethanol-induced Apoptosis in Human Neural Crest Cells Through Epigenetically Modulating The Expression of Anti-apoptotic Genes”. Y Li, F Yuan, T Wu, L Lu, J Liu, S-y Chen
“Exosomal shuttling of miR-126 from human neural crest cells mediated ethanol-induced repression of SDF1/CXCR4 and disruption of neural crest cell-placode interaction”. H Fan, F Yuan, T Wu, L Lu, JLiu, S-y Chen.
“Prenatal ethanol exposure induced global remodeling of the enhancer landscape in a zebrafish model of fetal alcohol spectrum disorders”. F Yuan, Y Yun, H Fan, L Lu, T Wu, J Liu, S-y Chen.
“Disruption of maternal folate-producing gut microbiota is associated with ethanol-induced folate deficiency and teratogenesis”. T Wu, F Yuan, Y Li, H Fan, L Lu, J Liu, S-y Chen
“Interaction of Heavy Drinking Patterns and Depression Severity Predicts Efficacy of Q!uetiapine Fumarate XR in Lovering Alcohol Intake in Alcohol Dependent Patients”. V Vatsalya, LM Marsano, KV Chandras, N Sinha, S Kumar, ML Schwandt, VA Ramchandani, CJ McClain
“Elevated Uric Acid is Associated with Liver Cell Death/Injury, Gut Barrier Dysfunction and Inflammation in Alcohol Dependents with Liver Injury”. V Vatsalya, F Li, N Shah, W Feng, CJ McClain
RSA 2019—Talks/Symposium Organizer:
Symposium Organizer: RSA 2019 Symposium: Alcohol and HIV-1 Induced Pathogenic Changes in the Gut-Liver-Brain Axis
Talk: “Metagenomic Analyses of the Gut-Microbial Dysbiosis Among HIV-Positive Heavy Drinkers” In: HIV, Alcohol and Comorbidity: From the Microbiome and Immunity to Clinical Outcomes.
Talk: “The role of alcohol and HIV-1 infection in gut and vaginal microbial dysbiosis in women and reproductive health”.
In: Alcohol and HIV: Building a Global Alcohol Research Agenda for Reproductive Health of People Affected by HIV/AIDS.
Talk: “Alcohol and HIV-1 Induced Pathogenic Changes in the Gut-Liver-Brain Axis”. In: HIV, Alcohol and Comorbidity: From the Microbiome and Immunity to Clinical Outcomes.
Symposium Organizer: RSA 2019 Symposium: Alcohol-induced alterations in the gut-liver axis: novel mechanistic insights into metabolic, immune, epithelial and microbial crosstalk.
Talk: “Beneficial Effects of Lowering Ω-6:Ω-3 PUFA Ratio on Ethanol-Mediated Alterations in the Intestinal Homeostasis, Gut Microbiome and Liver Injury in Mice”
Symposium Organizer and Discussant: RSA 2019 Symposium: Alcohol-induced alterations in the gut-liver axis: novel mechanistic insights into metabolic, immune, epithelial and microbial crosstalk.
Talk: “Nutrition:Alcohol:Gut/Microbiome Interactions and ALD” In: Translating Microbiota Research Into Clinical Practice for Alcoholic Hepatitis.