Department of Chemistry
University of Louisville
2320 South Brook Street
Louisville, KY 40292

Phone Numbers:
(502) 852-6798 (phone)
(502) 852-8149 (fax)

Mechanistic Enzymology

Phone: 502-852-5811
eugene.mueller@louisville.edu

Enzymology

tRNA Modification

Sulfur Transfer

Bioorganic Mechanism

Crystal Structure of Pseudouridine Synthase RluA: Indirect Sequence Readout through Protein-Induced RNA Structure
C. Hoang, J. Chen, C. A. Vizthum, J. M. Kandel, C. S. Hamilton, E. G. Mueller, and A. R. Ferré-d'Amaré
Mol. Cell 2006, 24, 535-545

Mechanistic Investigations of the Pseudouridine Synthase RluA Using RNA Containing 5-Fluorouridine
C. S. Hamilton, T. M. Greco, C. A. Vizthum, J. M. Ginter, M. V. Johnston, and E. G. Mueller
Biochemistry 2006, 39, 12019-12038

Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis
C. M. Wright, G. D. Christman, A. M. Snellinger, M. V. Johnston, and E. G. Mueller
Chem. Comm. 2006, 3104-3106

Trafficking in persulfides: delivering sulfur in biosynthetic pathways
E. G. Mueller
Nature Chem. Biol. 2006, 4, 185-194